Male fertility is affected by many factors, including diet, thyroid function and sex hormone levels. This test includes testosterone and FSH which are important hormones for sperm production, as well as a good overview of other health areas affecting fertility in men.Clinics & Availability
Why take this test?
It takes two to tango
Women often get most attention when fertility is concerned, but did you know that half of all infertility issues involve men? His Fertility is a good first step to check if your body condition is optimised to support the production of healthy sperms, and should be regarded as a complement to a semen analysis.
Do I need to fast?
You must not eat or drink anything other than water for at least 10 hours before the test. Testing in the morning is preferred.
No hidden costs
Everything from the in-clinic blood draw and tracked shipment of samples to the lab, through to delivery of the results and medical report is included in the price.
This test is performed as an in-clinic blood draw by a trained health professional and the samples are analysed by UKAS accredited labs.
Markers included in the analysis
Our medical team has designed the His Fertility to provide you with a comprehensive overview of blood markers relevant to male fertility. It includes 36 biomarkers across 6 health areas, and a personal medical report. Click on any of the health areas for a breakdown of the markers included. You can also click on each marker to learn more. Please note that this test should be taken while fasted, and only on weekdays (Monday - Friday).
Sperm production is regulated by reproductive hormones including testosterone, FSH and LH. Testosterone is the most important reproductive hormone in men, and its level decreases with increased age and body fat. Imbalances in the levels of reproductive hormones decrease fertility. Most of the testosterone circulating in the blood is bound to sex hormone-binding globulin (SHBG) and is considered inactive. The rest is weakly and reversibly bound to albumin. Calculation of unbound free testosterone level is included in this test. Free testosterone gives you a better picture of your testosterone status than total testosterone alone.
Health markersOestradiolFollicle Stimulating Hormone (FSH)Luteinising hormone (LH)ProlactinTotal testosteroneFree testosterone
The thyroid is a gland located in the neck that produces hormones that regulates the metabolism, how we use and store energy. The thyroid profile is used to evaluate thyroid function to diagnose and control hypothyroidism and hyperthyroidism. Undiagnosed thyroid dysfunction impairs fertility in both men and women. Hypothyroidism affects both the quantity and quality of sperms and also compromises the ability of the sperm to swim. Luckily, the negative effects of thyroid dysfunction can be relatively easily reversed once the condition is correctly diagnosed and successfully treated.
Health markersFree thyroxine (FT4)Thyroid-Stimulating Hormone (TSH)
Diabetes occurs when the body’s ability to regulate the amount of blood sugar (glucose) is impaired. In type 1 diabetes the body is no longer able to produce insulin, and in the more common type 2 (which occurs more frequently with age) the body is no longer sensitive to its action. Poor diet, lack of exercise and obesity increases the risk of both diabetes and infertility in both women and men. High blood sugar levels seen in diabetes lower testosterone levels impairing sperm production and also damage sperm DNA and thus decreasing sperm quality.
Vitamins and minerals are essential nutrients that are required by the body to work properly and stay healthy. There are 13 main types of vitamins – such as folate, and a number of minerals such as iron. Folate and vitamin B12 are both important for DNA synthesis and low levels can lead to decreased stability of sperm DNA which both decrease fertility and increase the risk of birth defects. Iron stores, as measured by ferritin, should be maintained within normal ranges as both high and low iron stores disturb the levels of reproductive hormones and thereby impair sperm production and fertility.
Health markersFerritinFolate (B9)Vitamin DVitamin B12
Most of the testosterone molecules in the blood are bound to proteins such as albumin and sex hormone binding globulin (SHBG). Binding to proteins inactivates the molecule and only the free unbound molecules are biologically active. Conditions that affect the levels of protein in the blood, such as dehydration/overhydration, low/high protein intake, liver or kidney disease can therefore affect the amount of free testosterone in the blood.
Health markersAlbuminSHBG (Sex Hormone Binding Globulin)
There are 3 main types of cells in the blood – platelets (important for stopping bleeding), white cells (to fight infection) and red cells (carries oxygen around the body). A full blood count is a good baseline test that can help diagnose a variety of conditions that can affect fertility, such as anaemia, infections and other blood disorders.
Health markersNumber of basophilsPercentage of basophilsPercentage of eosinophilsNumber of eosinophilsHaemoglobin (Hb)Leukocyte count (WBC)Number of lymphocytesPercentage of lymphocytesMean Corpuscular Haemoglobin Concentration (MCHC)Mean Corpuscular Haemoglobin (MCH)Mean Corpuscular Volume (MCV)Number of monocytesPercentage of monocytesMean Platelet Volume (MPV)Haematocrit (PCV)Red Blood Cell Count (RBC)Platelet Count (PLT)Red Cell Distribution Width (RDW)Number of neutrophilsPercentage of neutrophils
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