Monocyte count
Monocyte count

Monocyte count

May 3, 2022

Monocyte count

What is a monocyte count?

Monocytes are a type of white blood cell that comes from bone marrow. They can become either macrophage cells or dendritic cells.

Monocytes, along with other kinds of white blood cells, help the body fight disease and infection. When they become dendritic cells, they play a part in launching the inflammatory and anti-inflammatory processes that are part of your body’s immune response to infection. As macrophage cells, they can destroy microorganisms and foreign material, get rid of dead cells, and boost the body’s immune response.

Why is this analysis important?

Monocytes are the largest of the white blood cells and are about twiceTrusted Source the size of red blood cells. These powerful defenders aren’t plentiful in the bloodstream but they’re vital in protecting the body against infection.

Monocytes move throughout the bloodstream to the tissues in the body. They rest until needed and then transform into macrophages or dendritic cells. These are both different kinds of white blood cells.

Dendritic cells use receptors to show the antigens to other immune system cells. They can cause monocytes to travel through the body to the affected tissues.

Macrophages kill microorganisms and fight cancer cells. They also work with other white blood cells to remove dead cells and support the body’s immune system against foreign substances and infections.

One way macrophages do this is by signalling to other cell types that there is an infection. Together, several types of white blood cells then work to fight off the infection.

What are some of the causes of a high monocyte count?

Common conditions that could lead to a spike in abs monocytes can include:

  • Chronic inflammatory diseases, such as inflammatory bowel disease

  • Bacterial infections, such as tuberculosis, brucellosis, syphilis, and subacute bacterial endocarditis

  • Leukaemia and other types of cancer, including lymphoma and multiple myeloma

  • Sarcoidosis, a disease in which abnormal levels of inflammatory cells gather in multiple organs of the body

  • Langerhans cell histiocytosis, a rare disorder that can damage tissue in the body

What are some of the causes of a low monocyte count?

Low levels of monocytes tend to develop as a result of medical conditions that lower your overall white blood cell count or disease treatments that suppress the immune system.

Causes of low absolute monocyte count can include:

  • Chemotherapy and radiation therapy, which can injure bone marrow

  • HIV and AIDS, which weaken the body’s immune system

  • Sepsis, an infection of the bloodstream

    • Having low levels of monocytes may mean your body is more susceptible to infection.

    Other considerations

    In addition to monocytes, your blood contains other types of white blood cells, all of which help fight off infections and protect you from disease. The types of white blood cells fall into two main groups: granulocytes and mononuclear cells.