Mean Platelet Volume (MPV)

Mean Platelet Volume (MPV)

April 29, 2022

Mean Platelet Volume (MPV)

What is Mean Platelet Volume (MPV)?

MPV stands for mean platelet volume. Platelets are small blood cells that are essential for blood clotting, the process that helps you stop bleeding after an injury. An MPV blood test measures the average size of your platelets. The test can help diagnose bleeding disorders and diseases of the bone marrow.

Why is this analysis important?

An MPV blood test is used to help diagnose or monitor a variety of blood-related conditions. A test called a platelet count is often included with an MVP test. A platelet count measures the total number of platelets you have.

What are some of the causes of high Mean Platelet Volume (MPV)?

MPV results, along with platelet counts and other tests, can provide a more complete picture of the health of your blood. Depending on your platelet count and other blood measurements, an increased MPV result can indicate:

  • Thrombocytopenia, a condition in which your blood has a lower than normal number of platelets

  • Myeloproliferative disease, a type of blood cancer

  • Preeclampsia, a complication in pregnancy that causes high blood pressure. It usually starts after the 20th week of pregnancy.

  • Heart disease

  • Diabetes

What are some of the causes of low Mean Platelet Volume (MPV)?

  • A low MPV can indicate exposure to certain drugs that are harmful to cells.

  • It may also indicate marrow hypoplasia, a disorder that causes a decrease in blood cell production.

Other considerations

There are many factors that can affect the results of your MPV blood test. Living in high altitudes, strenuous physical activity, and certain drugs, such as birth control pills, may cause an increase in platelet levels. Decreased platelet levels may be caused by a women's menstrual cycle or pregnancy. In rare cases, platelets can be affected by a genetic defect.